Woohoo Hooniversity is probably my favourite dungeon in the game. I have to ask if there was that much exposed wire prior to Cackletta attacking, or if she ripped up the floors.
Being transformed into a monster whose life is agony by an evil witch's dark magic is a pretty good metaphor for how I felt during my last term at school.
Yo Bros are weird, I don't feel like they fit the SCIENCE aesthetic that the other enemies in hooniversity have, and they're koopas (in the remake they're shells are more obvious). One theory is that they're the hip young students, turned into evil turtles by Cackletta's magic and granted hip yoyos to style all over intruders.
(spoiled for size)
An interesting note about Laser Snifits and Yo Bros
like Rexes, both enemies have non-normal interactions with hands despite only appearing in an area you go to prior to learning hand techniques.